Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 12/20 | 0.32 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17832757 | 0.90 | KCNH2 (0.34) | MAPTRORCDDR1CNR2IRAK4 | |
| SCHEMBL20633529 | 0.88 | LRRK2 (0.35) | RORCCNR2 | |
| SCHEMBL29814294 | 0.88 | LRRK2 (0.35) | RORCCNR2 | |
| SCHEMBL22683346 | 0.87 | RORC (0.36) | RORCCTPS1SMN1; SMN2CNR2 | |
| SCHEMBL17824423 | 0.84 | MAPT (0.32) | MAPTRORCCTPS1IRAK4 | |
| SCHEMBL21869851 | 0.84 | CTPS1 (0.35) | MAPTRORCCTPS1DDR1CNR2 | |
| SCHEMBL17832754 | 0.83 | KCNH2 (0.35) | CNR2 | |
| SCHEMBL22683330 | 0.81 | CNR1 (0.36) | MAPTRORCCNR2 | |
| SCHEMBL30958305 | 0.81 | CNR1 (0.36) | MAPTRORCCNR2 | |
| SCHEMBL19366937 | 0.81 | SLC40A1 (0.36) | MAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| WO-2016091731-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | MAPT 407/4885RORC 1490/4885CTPS1 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.