Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 3/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | IKBKB | O14920 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | CHUK | O15111 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | TOP1 | P11387 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131720 | 0.92 | ACHE (0.62) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL12396546 | 0.90 | ACHE (0.61) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL15131722 | 0.86 | ACHE (0.58) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9043755 | 0.86 | PARP1 (0.81) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9042961 | 0.84 | PARP1 (0.76) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9040656 | 0.84 | PARP1 (0.81) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL121401 | 0.84 | ACHE (1.00) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29382084 | 0.84 | ACHE (1.00) | ACHEKDM4EALDH1A1GAAHPGD | |
| Hydrochloric Acid SCHEMBL4436954 | 0.82 | ACHE (0.96) | ACHEKDM4EALDH1A1GAAHPGD | |
| Hydrochloric Acid SCHEMBL3234011 | 0.82 | ACHE (0.96) | ACHEKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434239-B2 | Aza-dihydro-acridone derivatives | ARTAX BIOPHARMA INC. (US) | 2022-09-06 | — | — | US | claimed |
| US-11434239-B2 | Aza-dihydro-acridone derivatives | ARTAX BIOPHARMA INC. (US) | 2022-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434239-B2 | Aza-dihydro-acridone derivatives | CDKN1A, CD4, MKI67 | ACHE 4772/4885KDM4E 1211/4885ALDH1A1 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.