Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.81 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704720 | 0.89 | PARP1 (1.00) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL1478179 | 0.89 | PARP1 (1.00) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL9042961 | 0.88 | PARP1 (0.76) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL9040656 | 0.88 | PARP1 (0.81) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL29816631 | 0.86 | ACHE (0.72) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL2689488 | 0.84 | PARP1 (0.87) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL12396546 | 0.83 | ACHE (0.61) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL10134606 | 0.82 | PARP1 (0.79) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL1900370 | 0.81 | PARP1 (1.00) | PARP1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL3224273 | 0.79 | PARP1 (0.75) | PARP1KDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347831-B1 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1996-12-11 | — | — | EP | disclosed |