SCHEMBL29818641

SCHEMBL29818641

COc1ccc2cc(CC(C)N)ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.70
TAAR1 Q96RJ0 2/20 0.69
HTR2A P28223 2/20 0.66
HTR2C P28335 1/20 0.66
HTR2B P41595 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13484409 1.00 SLC6A4 (0.70) SLC6A4TAAR1HTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL11281141 0.98 SLC6A4 (0.68) SLC6A4TAAR1HTR2AHTR2CHTR2B
SCHEMBL13484112 0.85 PTGS1 (0.54) SLC6A4TAAR1
Hydrochloric Acid SCHEMBL11282729 0.83 HTR2A (0.62) SLC6A4TAAR1HTR2AHTR2CHTR2B
Para-Methoxyamphetamine SCHEMBL264634 0.83 SLC6A4 (1.00) SLC6A4TAAR1
Para-Methoxyamphetamine SCHEMBL394418 0.83 SLC6A4 (1.00) SLC6A4TAAR1
Para-Methoxyamphetamine SCHEMBL895775 0.83 SLC6A4 (1.00) SLC6A4TAAR1
SCHEMBL9546449 0.82 PTGS1 (0.56) TAAR1
SCHEMBL9546445 0.82 PTGS1 (0.56) TAAR1
SCHEMBL30824303 0.82 PTGS1 (0.56) SLC6A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683535-B Compound containing cyanoguanidine structure and preparation method and application thereof 中国药科大学 2022-08-30 CN disclosed