Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.39 |
| ▸ | ABAT | P80404 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950337 | 1.00 | KDM4E (0.44) | KDM4EPTGS2RAB9ACYP2A6ALDH5A1 | |
| SCHEMBL28333100 | 0.85 | KDM4E (0.44) | KDM4EPTGS2RAB9ACYP2A6ALDH5A1 | |
| SCHEMBL8715997 | 0.80 | CYP2A6 (0.50) | KDM4EPTGS2RAB9ACYP2A6ALDH1A1 | |
| SCHEMBL27593736 | 0.74 | ESR2 (0.50) | KDM4ERAB9AALDH1A1HSD17B10MEN1 | |
| SCHEMBL1420897 | 0.72 | MAPT (0.53) | KDM4ERAB9ACYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL28591091 | 0.71 | APP (0.46) | KDM4EALDH1A1HSD17B10MEN1POLB | |
| SCHEMBL11625132 | 0.71 | NQO1 (0.57) | KDM4EALDH1A1MEN1POLBMAPT | |
| SCHEMBL28829786 | 0.70 | TTR (0.54) | KDM4EPTGS2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL29826714 | 0.70 | TTR (0.54) | KDM4EPTGS2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL11337638 | 0.70 | CDK9 (0.46) | KDM4ERAB9ACYP2A6ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981263-B | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-114981263-A | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2022-08-30 | — | — | CN | disclosed |