SCHEMBL1420897

SCHEMBL1420897

O=Cc1ccc2oc3ccccc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
NPC1 O15118 4/20 0.53
HPGD P15428 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
RAB9A P51151 2/20 0.53
KIF11 P52732 2/20 0.49
AHR P35869 2/20 0.48
MAOA P21397 3/20 0.47
GLA P06280 1/20 0.47
CYP3A4 P08684 1/20 0.47
PGAM1 P18669 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP1A2 P05177 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8715997 0.90 CYP2A6 (0.50) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL2533931 0.89 MAPT (0.54) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL1784133 0.87 MAOA (0.62) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL1420747 0.81 MAPT (0.53) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL1784418 0.80 MAOA (0.62) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL11764173 0.80 TDP1 (0.47) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL19422630 0.79 NPC1 (0.54) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL13242794 0.79 ALDH1A1 (0.38) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL22335024 0.78 MAPT (0.50) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL26604316 0.78 MAPT (0.50) MAPTKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-12577263-B2 Compound and optical film comprising same LG CHEM, LTD. (KR) 2026-03-17 US disclosed
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
CN-114981277-B Compound and optical film comprising same 株式会社LG化学 2024-06-11 CN disclosed
WO-2024077078-A2 STERYLGLUCOSIDASE INHIBITING COMPOSITIONS AND METHOD OF USING THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-04-11 WO disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed
US-20230287008-A1 COMPOUND AND OPTICAL FILM COMPRISING SAME LG CHEM, LTD. (KR) 2023-09-14 US disclosed
US-20230287008-A1 COMPOUND AND OPTICAL FILM COMPRISING SAME LG CHEM, LTD. (KR) 2023-09-14 US disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed
US-4344956-A Oxotetrahydrothiophenes ERCOLI NICOLO 1982-08-17 US disclosed
US-4340624-A STYRYL-LIKE COMPOUNDS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-07-20 US disclosed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 US disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287008-A1 COMPOUND AND OPTICAL FILM COMPRISING SAME CDH1, OR10J3, CRY1 MAPT 212/4885KDM4E 1519/4885ALDH1A1 637/4885
US-12577263-B2 Compound and optical film comprising same NR2E3, CBR1, CBR3 MAPT 2350/4885KDM4E 2809/4885ALDH1A1 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.