Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040674 | 0.84 | CYP2D6 (0.40) | ELANESMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL1660887 | 0.82 | PAX8 (0.41) | PAX8LMNAMEN1KMT2AHPRT1 | |
| SCHEMBL29827543 | 0.82 | PAX8 (0.41) | PAX8LMNAMEN1KMT2AHPRT1 | |
| SCHEMBL10741200 | 0.78 | PAX8 (0.44) | PAX8HPRT1SLC40A1KEAP1ALDH1A1 | |
| Acetonitrile SCHEMBL28781302 | 0.76 | PAX8 (0.36) | PAX8SMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL8584659 | 0.73 | CYP2A6 (0.41) | ELANESMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL2574159 | 0.73 | CYP2A6 (0.50) | PAX8KMT2AHPRT1MAPTKEAP1 | |
| SCHEMBL14861459 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2LMNAKMT2ARAB9AALDH1A1 | |
| SCHEMBL2203473 | 0.71 | NPC1 (0.48) | ELANESMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL10904256 | 0.71 | PTPN22 (0.48) | MAPTSIGMAR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118688315-A | Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds | 复旦大学 | 2024-09-24 | — | — | CN | disclosed |
| US-20240286996-A1 | NAPHTHALENESULFONYL COMPOUNDS, AND PREPARATION METHODS AND APPLICATIONS | FUDAN UNIVERSITY (CN) | 2024-08-29 | — | — | US | disclosed |
| WO-2023016517-A1 | NAPHTHALENESULFONYL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 复旦大学 | 2023-02-16 | — | — | WO | disclosed |
| CN-113620847-B | Naphthalenesulfonyl compounds, preparation method and application thereof | 复旦大学 | 2022-08-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240286996-A1 | NAPHTHALENESULFONYL COMPOUNDS, AND PREPARATION METHODS AND APPLICATIONS | ABCG2, TST, STS | PAX8 4344/4885ELANE 1315/4885SMN1; SMN2 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.