Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2982932 | 1.00 | MAPT (0.51) | MAPTHTTLMNAKDM4ESTAT3 | |
| SCHEMBL9356442 | 0.80 | LMNA (0.41) | LMNAKDM4ECA1CA2ALDH1A1 | |
| SCHEMBL2981997 | 0.80 | KMT2A (0.53) | LMNAKDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL2981993 | 0.80 | KMT2A (0.53) | LMNAKDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11542934 | 0.79 | SMN1; SMN2 (0.56) | MAPTHTTLMNACA1CA2 | |
| SCHEMBL2982687 | 0.79 | CNR2 (0.46) | MAPTHTTLMNACA1CA2 | |
| SCHEMBL2982682 | 0.79 | CNR2 (0.46) | MAPTHTTLMNACA1CA2 | |
| SCHEMBL11541849 | 0.76 | ALDH1A1 (0.56) | MAPTHTTLMNAKDM4ECA1 | |
| SCHEMBL939646 | 0.75 | MMP2 (0.40) | MAPTHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10857529 | 0.75 | MAPT (0.52) | MAPTHTTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781613-B2 | Substituted N-aminomethylene sulfonamides, production and use thereof as medicaments | SANOFI-AVENTIS (FR) | 2010-08-24 | — | — | US | claimed |
| US-7781613-B2 | Substituted N-aminomethylene sulfonamides, production and use thereof as medicaments | SANOFI-AVENTIS (FR) | 2010-08-24 | — | — | US | disclosed |
| US-20080069851-A1 | SUBSTITUTED N-AMINOMETHYLENE SULFONAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080069851-A1 | SUBSTITUTED N-AMINOMETHYLENE SULFONAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | LIPE, STS, ARSA | MAPT 4769/4885HTT 3896/4885LMNA 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.