SCHEMBL29831896

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)N)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	2/20	0.55

▸	OPRK1	P41145	2/20	0.53

▸	CCKBR	P32239	8/20	0.53

▸	CCKAR	P32238	1/20	0.52

▸	TFPI	P10646	1/20	0.52

▸	OPRM1	P35372	1/20	0.51

▸	OPRD1	P41143	1/20	0.51

▸	TACR3	P29371	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Tyrlysseraspserphetyrglyleumet SCHEMBL30475005	0.93	OPRM1 (0.61)	IL23ROPRK1CCKBRTFPIOPRM1
SCHEMBL29696462	0.90	OPRM1 (0.60)	IL23ROPRK1TFPIOPRM1OPRD1
SCHEMBL31433308	0.87	IL23R (0.50)	IL23ROPRK1OPRM1OPRD1
SCHEMBL29723863	0.87	NPY1R (0.50)	IL23ROPRK1CCKBRCCKAROPRM1
SCHEMBL29678561	0.85	CCKAR (0.51)	OPRK1CCKBRCCKARTFPIOPRM1
SCHEMBL11414413	0.84	OPRD1 (0.65)	OPRK1CCKBRCCKAROPRM1OPRD1
SCHEMBL29856025	0.84	TFPI (0.56)	IL23ROPRK1CCKBRTFPIOPRM1
SCHEMBL30432263	0.84	CCKBR (0.52)	IL23RCCKBRCCKAR
SCHEMBL31433314	0.84	OPRM1 (0.48)	IL23ROPRK1TFPIOPRM1OPRD1
SCHEMBL30618464	0.83	IL23R (0.50)	IL23ROPRK1CCKBRCCKARTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220281989-A1	GPCR BINDING PROTEINS AND SYNTHESIS THEREOF	Twist Bioscience Corporation	2022-09-08	—	—	US	disclosed
US-11407837-B2	GPCR binding proteins and synthesis thereof	Twist Bioscience Corporation (US)	2022-08-09	—	—	US	disclosed