SCHEMBL29832008

SCHEMBL29832008

O=C(c1ccccc1)C(CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 0.48
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MITF O75030 2/20 0.44
ATM Q13315 2/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GFER P55789 1/20 0.44
PAX8 Q06710 1/20 0.44
LMNA P02545 4/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTPN2 P17706 1/20 0.43
CES1 P23141 2/20 0.42
CES2 O00748 1/20 0.42
CYP1A1 P04798 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAPT P10636 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29831769 0.90 ALDH1A1 (0.42) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29832463 0.90 NTSR1 (0.49) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29831753 0.90 NTSR1 (0.43) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29832000 0.90 HSP90AA1 (0.42) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29832144 0.90 NTSR1 (0.47) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29832039 0.90 LMNA (0.46) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29832444 0.89 NTSR1 (0.48) PTPN1ALDH1A1SMN1; SMN2MITFATM
SCHEMBL29831903 0.87 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2MITFHTTRAB9A
SCHEMBL29832215 0.87 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MITFHTTRAB9A
SCHEMBL29832142 0.84 PTPN1 (0.52) PTPN1ALDH1A1SMN1; SMN2MITFATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093367-A Preparation method and application of fluoroalkyl ketone compound 华南农业大学 2022-09-23 CN disclosed