SCHEMBL29833552

SCHEMBL29833552

CC(=O)C(=Cc1ccccc1O)C(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
HIF1A Q16665 1/20 0.69
LMNA P02545 3/20 0.54
MAPT P10636 3/20 0.54
ALDH1A1 P00352 3/20 0.54
KMT2A Q03164 2/20 0.54
GAA P10253 1/20 0.54
CES2 O00748 5/20 0.50
CES1 P23141 4/20 0.50
NFKB1 P19838 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
JUN P05412 1/20 0.41
NFE2L2 Q16236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4924930 1.00 CYP3A4 (0.69) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL4924923 1.00 CYP3A4 (0.69) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL4924447 0.86 MAPT (0.55) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL11052877 0.83 MAPT (0.49) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL11052862 0.83 MAPT (0.49) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL11505978 0.79 MAPT (0.49) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL8464899 0.77 MAPT (0.61) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL8464902 0.77 MAPT (0.61) CYP3A4CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL7607193 0.76 NFKB1 (0.53) LMNAMAPTALDH1A1NFKB1CA1
SCHEMBL11203025 0.74 MAPT (0.46) CYP3A4LMNAMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288022-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-12-13 EP disclosed
WO-2022167123-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-08-11 WO disclosed