Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924930 | 1.00 | CYP3A4 (0.69) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL29833552 | 1.00 | CYP3A4 (0.69) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL4924447 | 0.86 | MAPT (0.55) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL11052877 | 0.83 | MAPT (0.49) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL11052862 | 0.83 | MAPT (0.49) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL11505978 | 0.79 | MAPT (0.49) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL8464899 | 0.77 | MAPT (0.61) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL8464902 | 0.77 | MAPT (0.61) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7607193 | 0.76 | NFKB1 (0.53) | LMNAMAPTALDH1A1NFKB1CA1 | |
| SCHEMBL11203025 | 0.74 | MAPT (0.46) | CYP3A4LMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | claimed |
| EP-1838278-A1 | 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | Givaudan SA (CH) | 2007-10-03 | — | — | EP | claimed |
| WO-2006076821-A1 | 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | GIVAUDAN SA (CH) | 2006-07-27 | — | — | WO | claimed |
| US-20240041752-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-02-08 | — | — | US | disclosed |
| EP-4039244-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2022-08-10 | — | — | EP | disclosed |
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | TYR, MAL2, ACMSD | CYP3A4 1515/4885CYP1A2 429/4885CYP2C9 436/4885 |
| US-20240041752-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | AOX1, TYR, OCIAD1 | CYP3A4 282/4885CYP1A2 70/4885CYP2C9 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.