Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966151 | 0.87 | HDAC1 (0.58) | HDAC1SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL18152960 | 0.87 | HDAC1 (0.48) | HDAC1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL2925453 | 0.86 | HDAC1 (0.61) | HDAC1SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL4078006 | 0.85 | SMN1; SMN2 (0.60) | HDAC1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL15598651 | 0.84 | SMN1; SMN2 (0.69) | HDAC1SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL9821067 | 0.83 | POLB (0.69) | HDAC1SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL17244480 | 0.83 | HDAC1 (0.58) | HDAC1SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL863069 | 0.82 | RAB9A (0.58) | HDAC1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL30368269 | 0.82 | RAB9A (0.58) | HDAC1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL9821015 | 0.82 | ALDH1A1 (0.48) | HDAC1SMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110668948-B | Preparation method of 4-chloro-2-fluoro-5-nitroacetophenone | 苏州敬业医药化工有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-110668948-A | Preparation method of 4-chloro-2-fluoro-5-nitroacetophenone | 苏州敬业医药化工有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-110668948-B | Preparation method of 4-chloro-2-fluoro-5-nitroacetophenone | 苏州敬业医药化工有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111072513-B | Preparation method of hepatitis drug intermediate | 苏州敬业医药化工有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111072513-A | Preparation method of hepatitis drug intermediate | 苏州敬业医药化工有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110668948-A | Preparation method of 4-chloro-2-fluoro-5-nitroacetophenone | 苏州敬业医药化工有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-7786155-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-08-31 | — | — | US | disclosed |
| EP-2212314-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | Novartis AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| EP-2212295-A2 | 4-PHENYL-5-OXO-IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEROF | Novartis AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009050201-A2 | 4-PHENYL-5-OXO-IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEROF | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050200-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099243-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
| US-20090099244-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099244-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLC10A6, SLCO1B1 | HDAC1 671/4885SMN1; SMN2 4082/4885NPC1 464/4885 |
| US-20090099243-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLCO1B1, SLCO1B3 | HDAC1 750/4885SMN1; SMN2 3920/4885NPC1 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.