Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689610 | 0.84 | L3MBTL1 (0.62) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30618513 | 0.83 | L3MBTL1 (0.75) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5426936 | 0.83 | L3MBTL1 (0.75) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19818456 | 0.83 | KAT6A (0.50) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3655101 | 0.82 | KDM4E (0.59) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL21020967 | 0.82 | HDAC8 (0.59) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL26217054 | 0.81 | TP53BP1 (0.72) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20206540 | 0.81 | ACHE (0.55) | TP53BP1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL18175984 | 0.81 | KDM4E (0.54) | L3MBTL1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL14234253 | 0.80 | KAT6A (0.52) | L3MBTL1TP53BP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |