Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17032313 | 0.83 | CNR2 (0.48) | ALDH1A1KMT2AMEN1RAB9AHSD17B10 | |
| SCHEMBL21020967 | 0.82 | HDAC8 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3655101 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL5906529 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1KMT2AMEN1PTGS1 | |
| SCHEMBL29944886 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1KMT2AMEN1PTGS1 | |
| SCHEMBL10630944 | 0.81 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL29836705 | 0.81 | L3MBTL1 (0.67) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL20206540 | 0.81 | ACHE (0.55) | ALDH1A1KMT2AMEN1RAB9AHSD17B10 | |
| SCHEMBL12852621 | 0.79 | NAMPT (0.47) | KMT2AMEN1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL6160025 | 0.79 | MAPK1 (0.60) | KDM4EALDH1A1KMT2AMEN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |