Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | TYR | P14679 | 2/20 | 0.54 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685892 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BTYRITGAVTACR1 | |
| SCHEMBL28806164 | 0.96 | ITGB3 (0.53) | ITGB3ITGA2BTYRTACR1CTSL | |
| SCHEMBL28806163 | 0.96 | ITGB3 (0.53) | ITGB3ITGA2BTYRTACR1CTSL | |
| SCHEMBL9744259 | 0.93 | TYR (0.58) | ITGB3ITGA2BTYRTACR1CTSL | |
| SCHEMBL23086011 | 0.91 | CTSL (0.52) | ITGB3ITGA2BTYRTACR1CTSL | |
| SCHEMBL3643477 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BTYRITGAVTACR1 | |
| SCHEMBL3643481 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BTYRITGAVTACR1 | |
| SCHEMBL27001675 | 0.90 | CAPN1 (0.60) | CTSLCTSBCTSS | |
| SCHEMBL27132012 | 0.90 | CAPN1 (0.60) | CTSLCTSBCTSS | |
| SCHEMBL9825306 | 0.90 | ITGA4 (0.57) | ITGB3ITGA2BTYRITGAVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022191338-A1 | LEVODOPA-PRODRUGS AND CARBIDOPA-PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2022-09-15 | — | — | WO | disclosed |