Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 8/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838969 | 0.91 | CNR1 (0.47) | CA1CA2POLBCNR1PPARA | |
| SCHEMBL29838971 | 0.87 | POLB (0.59) | POLBCNR1PPARACNR2TP53 | |
| SCHEMBL29838966 | 0.87 | POLB (0.59) | POLBCNR1PPARACNR2TP53 | |
| SCHEMBL29838887 | 0.86 | CNR1 (0.45) | CA1CA2POLBCNR1PPARA | |
| SCHEMBL29838940 | 0.86 | PIN1 (0.47) | CA1CA2POLBCNR1CNR2 | |
| SCHEMBL29838943 | 0.79 | POLB (0.56) | POLBCNR1PPARACNR2ALDH1A1 | |
| SCHEMBL29838929 | 0.78 | KDM4E (0.50) | CA1CA2POLBALDH1A1NPSR1 | |
| SCHEMBL29838947 | 0.75 | CNR1 (0.81) | CNR1PPARACNR2 | |
| SCHEMBL29838949 | 0.75 | CNR1 (0.81) | CNR1PPARACNR2 | |
| SCHEMBL277080 | 0.74 | CNR1 (0.54) | POLBCNR1CNR2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164239-A1 | PYRAZOLE-CARBOXAMIDE DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 파미노젠 | 2022-08-04 | — | — | WO | disclosed |