Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277032 | 0.88 | KDM4E (0.51) | KDM4EMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL29838940 | 0.87 | PIN1 (0.47) | KDM4EMAPTCA1CA2ALDH1A1 | |
| SCHEMBL29838942 | 0.84 | ALDH1A1 (0.63) | KDM4EMAPTKMT2ACA1CA2 | |
| SCHEMBL4187519 | 0.83 | CA1 (0.58) | KDM4EMAPTKMT2ACA1CA2 | |
| SCHEMBL29838969 | 0.80 | CNR1 (0.47) | KDM4EMAPTCA1CA2ALDH1A1 | |
| SCHEMBL29838938 | 0.78 | CA1 (0.50) | KDM4EMAPTKMT2AMEN1CA1 | |
| SCHEMBL4872470 | 0.77 | GABRA2 (0.59) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL14660158 | 0.76 | KDM4E (0.79) | KDM4EMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL2919412 | 0.76 | ALDH1A1 (0.73) | KDM4EMAPTCA1CA2ALDH1A1 | |
| SCHEMBL327857 | 0.75 | CNR1 (0.53) | KDM4EMAPTKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164239-A1 | PYRAZOLE-CARBOXAMIDE DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 파미노젠 | 2022-08-04 | — | — | WO | disclosed |