Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838938 | 0.91 | CA1 (0.50) | CNR1PPARACNR2POLBCA1 | |
| SCHEMBL29838943 | 0.86 | POLB (0.56) | CNR1PPARACNR2POLBALDH1A1 | |
| SCHEMBL29838887 | 0.85 | CNR1 (0.45) | CNR1PPARACNR2POLBCA1 | |
| SCHEMBL29838940 | 0.81 | PIN1 (0.47) | CNR1CNR2POLBCA1CA2 | |
| SCHEMBL29838929 | 0.80 | KDM4E (0.50) | POLBCA1CA2ALDH1A1NPSR1 | |
| SCHEMBL29838966 | 0.78 | POLB (0.59) | CNR1PPARACNR2POLBTP53 | |
| SCHEMBL29838971 | 0.78 | POLB (0.59) | CNR1PPARACNR2POLBTP53 | |
| SCHEMBL29838948 | 0.76 | CNR1 (0.79) | CNR1PPARACNR2 | |
| SCHEMBL29838900 | 0.71 | CNR1 (0.53) | CNR1PPARACNR2POLB | |
| SCHEMBL182215 | 0.70 | SIRT5 (0.43) | PPARAPLAUALDH1A1NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164239-A1 | PYRAZOLE-CARBOXAMIDE DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 파미노젠 | 2022-08-04 | — | — | WO | disclosed |