Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729600 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL29839301 | 0.90 | MGLL (0.41) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL22729560 | 0.90 | MGLL (0.41) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL23116386 | 0.87 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL23116378 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL22754902 | 0.87 | SLC6A2 (0.36) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL22729439 | 0.86 | KDM4E (0.35) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL22729609 | 0.86 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL29839278 | 0.86 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 | |
| SCHEMBL29839348 | 0.86 | KDM4E (0.35) | ALDH1A1MAPTHSD17B10NPSR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | ALDH1A1 2660/4885MAPT 364/4885HSD17B10 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.