Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16929982 | 1.00 | PPARG (0.40) | PPARGCA2PPARDPPARAKDM4E | |
| SCHEMBL17721710 | 0.88 | PPARA (0.38) | PPARGCA2PPARDPPARAKDM4E | |
| SCHEMBL19087207 | 0.88 | PPARA (0.38) | PPARGCA2PPARDPPARAKDM4E | |
| SCHEMBL16930243 | 0.85 | REN (0.48) | PPARAMAPTLMNAHTTMEN1 | |
| SCHEMBL16930147 | 0.83 | KDM4E (0.41) | CA2PPARDPPARAKDM4EMAPK1 | |
| SCHEMBL29840555 | 0.83 | KDM4E (0.41) | CA2PPARDPPARAKDM4EMAPK1 | |
| SCHEMBL19815542 | 0.82 | PPARA (0.41) | PPARGPPARDPPARAKDM4EMAPK1 | |
| SCHEMBL21175742 | 0.82 | CA2 (0.39) | CA2KDM4EALDH1A1HPGD | |
| SCHEMBL8285816 | 0.80 | ALDH1A1 (0.43) | KDM4EMAPK1MAPTATMLMNA | |
| SCHEMBL16929923 | 0.80 | CA2 (0.38) | PPARGCA2PPARDPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715624-B | Novel therapeutic agents for the treatment of HBV infection | 广州麓鹏制药有限公司 | 2022-08-16 | — | — | CN | disclosed |