Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.62 |
| ▸ | CA2 | P00918 | 8/20 | 0.62 |
| ▸ | CA9 | Q16790 | 8/20 | 0.62 |
| ▸ | CA5A | P35218 | 5/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.48 |
| ▸ | CA7 | P43166 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CA6 | P23280 | 4/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449580 | 0.82 | TSHR (0.50) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL13064454 | 0.81 | CA1 (0.63) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL4573294 | 0.80 | CA2 (0.62) | CA1CA2CA9CA5AKIF11 | |
| SCHEMBL514597 | 0.80 | RECQL (0.48) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL9464709 | 0.79 | CA2 (0.45) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL2444207 | 0.78 | CA2 (0.60) | CA1CA2CA9CA5AKIF11 | |
| SCHEMBL1645091 | 0.78 | CA1 (0.60) | CA1CA2CA9CA5AKIF11 | |
| SCHEMBL22266022 | 0.78 | CA2 (0.61) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL22266036 | 0.78 | CA2 (0.60) | CA1CA2CA9CA5ARECQL | |
| SCHEMBL2461753 | 0.78 | RECQL (0.47) | CA1CA2CA9CA5ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379781-C | Polyoxazolidone adhesive resin compoistion prepared from polyepoxides and polyisocyanates | DOW CHEMICAL CO (US) | 2008-04-09 | — | — | CN | claimed |
| EP-1137683-B1 | POLYOXAZOLIDONE ADHESIVE RESIN COMPOSITION PREPARED FROM POLYEPOXIDES AND POLYISOCYANATES | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-08-17 | — | — | EP | claimed |
| US-6432541-B1 | RESIN IMPREGNATED PREPREGS; METALLIC FOILS COATED WITH ADHESIVE | DOW GLOBAL TECHNOLOGIES INC. | 2002-08-13 | — | — | US | claimed |
| CN-1333791-A | Polyoxazolidone adhesive resin compoistion prepared from polyepoxides and polyisocyanates | DOW CHEMICAL CO (US) | 2002-01-30 | — | — | CN | claimed |
| EP-1137683-A1 | POLYOXAZOLIDONE ADHESIVE RESIN COMPOSITION PREPARED FROM POLYEPOXIDES AND POLYISOCYANATES | THE DOW CHEMICAL COMPANY (US) | 2001-10-04 | — | — | EP | claimed |
| WO-2000034351-A1 | POLYOXAZOLIDONE ADHESIVE RESIN COMPOSITION PREPARED FROM POLYEPOXIDES AND POLYISOCYANATES | THE DOW CHEMICAL COMPANY (US) | 2000-06-15 | — | — | WO | claimed |
| US-12303544-B2 | Cytotoxic and anti-mitotic compounds, and methods of using the same | ZYMEWORKS BC INC. (CA) | 2025-05-20 | — | — | US | disclosed |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners (US) | 2025-04-01 | — | — | US | disclosed |
| EP-4522618-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | Merck Patent GmbH (DE) | 2025-03-19 | — | — | EP | disclosed |
| US-12195490-B2 | STRAD-binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-14 | — | — | US | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20230390354-A1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | ZYMEWORKS BC INC. (CA) | 2023-12-07 | — | — | US | disclosed |
| CN-110143999-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活英属哥伦比亚省公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-1998049214-A1 | NITROGEN-CONTAINING EPOXY RESINS FOR PHOTOCURABLE COATING APPLICATIONS | THE DOW CHEMICAL COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| US-5767283-A | CHEMICAL INTERMEDIATE FOR 7-N-ORGANOSULFONYL-1H-INDOLE DERIVATIVE ANTITUMOR AGENTS; NONTOXIC | EISAI CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5721246-A | ANTITUMOR AGENTS; LOW TOXICITY | EISAI CO., LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| EP-0673937-A1 | BICYCLIC HETEROCYCLIC SULFONAMIDE AND SULFONIC ESTER DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-4816470-A | Heterocyclic compounds | GLAXO GROUP LIMITED | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12303544-B2 | Cytotoxic and anti-mitotic compounds, and methods of using the same | CCNB1, PLK1, BOD1L1 | CA1 2505/4885CA2 3603/4885CA9 2932/4885 |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | PDXK, DTYMK, HIPK1 | CA1 4423/4885CA2 4431/4885CA9 3509/4885 |
| US-20230390354-A1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | CCNB1, PLK1, BOD1L1 | CA1 2505/4885CA2 3603/4885CA9 2932/4885 |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CA1 4346/4885CA2 2235/4885CA9 2390/4885 |
| US-12195490-B2 | STRAD-binding agents and uses thereof | STRAP, STRA6, PLAUR | CA1 3508/4885CA2 2899/4885CA9 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.