Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692490 | 0.94 | CA2 (0.44) | CA2CA1CA9CA5ARECQL | |
| SCHEMBL1764709 | 0.82 | CA1 (0.57) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL17374931 | 0.79 | CA2 (0.48) | CA2CA1CA9CA5AALDH1A1 | |
| SCHEMBL2984207 | 0.79 | CA1 (0.62) | CA2CA1CA9CA5ARECQL | |
| SCHEMBL2464599 | 0.76 | CA1 (0.59) | CA2CA1CA9CA5ARECQL | |
| SCHEMBL25370014 | 0.74 | CYP19A1 (0.56) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL30014410 | 0.74 | CYP19A1 (0.56) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL22050430 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL17375010 | 0.73 | CA2 (0.38) | CA2CA1CA9CA5AKIF11 | |
| SCHEMBL12643529 | 0.73 | LOXL2 (0.56) | CA2CA1CA9CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204453-A | Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |