SCHEMBL1449580

SCHEMBL1449580

Nc1ccc(CS(=O)(=O)Cc2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
CYP3A4 P08684 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.50
GFER P55789 1/20 0.50
RECQL P46063 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
LMNA P02545 1/20 0.46
MPO P05164 1/20 0.46
CYP2C9 P11712 1/20 0.46
HTR6 P50406 1/20 0.46
CA1 P00915 6/20 0.45
CA2 P00918 6/20 0.45
CA9 Q16790 6/20 0.45
CA12 O43570 4/20 0.45
CA14 Q9ULX7 3/20 0.45
CA7 P43166 3/20 0.44
CA5A P35218 3/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3442462 0.88 GAA (0.48) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL1202589 0.83 RECQL (0.46) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL514597 0.82 RECQL (0.48) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL2984207 0.82 CA1 (0.62) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL999563 0.80 FAAH (0.60) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL2461753 0.80 RECQL (0.47) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL1335821 0.80 TSHR (0.50) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL514596 0.80 RECQL (0.47) TSHRCYP3A4TDP1ALDH1A1GFER
Hydrochloric Acid SCHEMBL1056876 0.78 FAAH (0.58) TSHRCYP3A4TDP1ALDH1A1GFER
SCHEMBL18868426 0.78 GAA (0.59) TSHRCYP3A4TDP1ALDH1A1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070618-A Graphite-based electrochemical cell 铌博尔特有限公司 2026-05-19 CN disclosed
CN-118120070-A Electrode coating method and coated electrode 剑桥企业有限公司 2024-05-31 CN disclosed
EP-4261037-A1 EPOXY RESIN COMPOSITION, CURED PRODUCT THEREOF, AND LAMINATE DIC Corporation (JP) 2023-10-18 EP disclosed
EP-3854848-B1 RESIN COMPOSITION, CURED OBJECT, AND LAMINATE DAINIPPON INK & CHEMICALS (JP) 2023-01-25 EP disclosed
EP-2268712-B1 POLYETHERIMIDE AND POLYETHERIMIDE SULFONE BLENDS HAVING AUTOMOTIVE LIGHTING APPLICATIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-04-05 EP disclosed
CN-106458906-A Novel pyridone colorants 科莱恩国际有限公司 2017-02-22 CN disclosed
CN-106414616-A Pyridone dye composition 科莱恩国际有限公司 2017-02-15 CN disclosed
US-8513265-B2 [6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2013-08-20 US disclosed
US-20130116237-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2013-05-09 US disclosed
US-8314095-B2 [6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2012-11-20 US disclosed
US-8076322-B2 [6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2011-12-13 US disclosed
US-20110136783-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY 2011-06-09 US disclosed
US-7910583-B2 [6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2011-03-22 US disclosed
EP-2144902-A1 [6,6]AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS Bristol-Myers Squibb Company (US) 2010-01-20 EP disclosed
US-20080293690-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY 2008-11-27 US disclosed
WO-2008137435-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-13 WO disclosed
CN-1332944-C Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate SHANGHAI INST ORGANIC CHEM (CN) 2007-08-22 CN disclosed
CN-1651408-A Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate SHANGHAI INST ORGANIC CHEM (CN) 2005-08-10 CN disclosed
US-4329283-A DISPERSE DYES BAYER AKTIENGESELLSCHAFT (DE) 1982-05-11 US disclosed
US-3998802-A POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES BASF AKTIENGESELLSCHAFT (DT) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136783-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS GPR119, GPR6, GPR139 TSHR 420/4885CYP3A4 1080/4885TDP1 3985/4885
US-20130116237-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS GPR119, GPR6, GPR139 TSHR 420/4885CYP3A4 1080/4885TDP1 3985/4885
US-20080293690-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS GPR119, GPR6, GPR139 TSHR 420/4885CYP3A4 1080/4885TDP1 3985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.