Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285807 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL16536963 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL26676116 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL16536117 | 0.68 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL16536004 | 0.68 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL16543633 | 0.68 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7298112 | 0.67 | MAOA (0.46) | KDM4EHPGDSMN1; SMN2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL16536006 | 0.67 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL15099945 | 0.65 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL9213813 | 0.65 | PPARG (0.55) | KDM4EALDH1A1KMT2AMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343046-A | Novel 3-oxo-4-substituted aryl-3, 4-dihydropyrazine-2-carboxamide compound and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-111440177-B | Substituted pyrazolo [1,5-a ] pyrimidine compound and preparation method and application thereof | 辽宁大学 | 2022-06-14 | — | — | CN | disclosed |