Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL273260 | 0.79 | CYP1A2 (1.00) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL10486461 | 0.79 | CYP1A2 (1.00) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL3416 | 0.79 | CYP1A2 (1.00) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL29767730 | 0.79 | CYP1A2 (1.00) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL7207908 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL7608382 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL11319254 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL21490911 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL9850309 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU | |
| 1-Naphthol SCHEMBL9169707 | 0.77 | CYP1A2 (0.94) | CYP1A2CTDSP1PTPN22KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188728-A9 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-08-11 | — | — | WO | disclosed |