Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578099 | 1.00 | LMNA (0.40) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL23588038 | 0.89 | ALDH1A1 (0.43) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL29974028 | 0.86 | MEN1 (0.39) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL23578283 | 0.86 | MEN1 (0.39) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL25299009 | 0.85 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29843966 | 0.83 | L3MBTL1 (0.46) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL25297027 | 0.83 | L3MBTL1 (0.46) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL23588168 | 0.82 | MAPT (0.40) | TSHRMAPK1TDP1KMT2AALDH1A1 | |
| SCHEMBL23588331 | 0.80 | ALDH1A1 (0.43) | LMNATSHRMAPK1TDP1MEN1 | |
| SCHEMBL23578251 | 0.79 | MAPT (0.45) | LMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066418-A | Carboxy derivatives with anti-inflammatory properties | 西特瑞治疗有限公司 | 2022-09-16 | — | — | CN | claimed |
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |
| CN-115066418-A | Carboxy derivatives with anti-inflammatory properties | 西特瑞治疗有限公司 | 2022-09-16 | — | — | CN | disclosed |