Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578283 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAAPLNRPPARG | |
| SCHEMBL25801788 | 0.90 | ALDH1A1 (0.36) | APLNRPPARGTSHRALDH1A1MAPT | |
| SCHEMBL25801811 | 0.87 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL29844170 | 0.86 | LMNA (0.40) | MEN1KMT2ALMNAAPLNRPPARG | |
| SCHEMBL23578099 | 0.86 | LMNA (0.40) | MEN1KMT2ALMNAAPLNRPPARG | |
| SCHEMBL23588068 | 0.85 | SPHK2 (0.42) | KMT2ALMNATSHRMAPK1TDP1 | |
| SCHEMBL25801971 | 0.84 | MAPT (0.35) | MEN1KMT2ATSHRKDM4EL3MBTL1 | |
| SCHEMBL25801910 | 0.82 | MAPT (0.41) | LMNAPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL23578293 | 0.82 | TSHR (0.38) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL29973191 | 0.82 | TSHR (0.38) | MEN1KMT2ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |