Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | LPL | P06858 | 4/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750211 | 0.76 | KDM1A (0.38) | KDM1APRCPDRD2DRD1EGFR | |
| SCHEMBL19194249 | 0.71 | LPL (0.41) | LPLLIPGHIF1A | |
| SCHEMBL20952603 | 0.68 | BACE1 (0.35) | EGFRBACE1LPLLIPG | |
| SCHEMBL16831298 | 0.68 | F11 (0.38) | DRD2BACE1LPLLIPG | |
| SCHEMBL30935345 | 0.68 | LPL (0.35) | KDM1ADRD1EGFRBACE1LPL | |
| SCHEMBL24820904 | 0.67 | LPL (0.40) | DRD2BACE1LPLLIPG | |
| SCHEMBL19752317 | 0.67 | PRCP (0.55) | KDM1APRCP | |
| SCHEMBL19561505 | 0.67 | HIF1A (0.34) | LPLLIPGHIF1A | |
| SCHEMBL17948747 | 0.66 | ASIC3 (0.46) | DRD2LPLLIPG | |
| SCHEMBL31371681 | 0.66 | ASIC3 (0.46) | DRD2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028639-A | Pyrrolo [2,3-b ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2022-09-09 | — | — | CN | disclosed |