Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.36 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.36 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19066923 | 0.91 | THRB (0.53) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL14438898 | 0.90 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Bromide SCHEMBL29236904 | 0.88 | THRB (0.53) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5272116 | 0.81 | THRB (0.46) | THRBTSHRHPGDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5894195 | 0.81 | LMNA (0.49) | TSHRCYP3A4CYP1A2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL3910414 | 0.81 | TP53 (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28037622 | 0.79 | THRB (0.44) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL14409026 | 0.79 | THRB (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| Bromide SCHEMBL30923513 | 0.79 | THRB (0.46) | THRBTSHRHPGDALDH1A1CYP1A2 | |
| SCHEMBL31509674 | 0.79 | THRB (0.58) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421788-A | Laminated film | 三菱化学株式会社 | 2025-02-11 | — | — | CN | disclosed |
| WO-2024053554-A1 | LIQUID COMPOSITION AND METHOD FOR PRODUCING LAMINATE USING LIQUID COMPOSITION | ＡＧＣ株式会社 | 2024-03-14 | — | — | WO | disclosed |
| WO-2024005216-A1 | LAMINATED FILM | 三菱ケミカル株式会社 | 2024-01-04 | — | — | WO | disclosed |
| WO-2022124202-A1 | COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT | 株式会社クラレ | 2022-06-16 | — | — | WO | disclosed |