Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30887472 | 0.86 | ESR1 (0.54) | ESR1ESR2CHRNA7 | |
| SCHEMBL6464770 | 0.79 | CA2 (0.49) | CA1CA2 | |
| SCHEMBL634750 | 0.75 | ESR1 (0.68) | ESR1ESR2DRD2DRD3OPRK1 | |
| SCHEMBL30513304 | 0.73 | ESR1 (0.61) | ESR1ESR2DRD2DRD3OPRK1 | |
| SCHEMBL3269864 | 0.73 | ESR1 (0.61) | ESR1ESR2DRD2DRD3OPRK1 | |
| SCHEMBL27937706 | 0.73 | ESR1 (0.61) | ESR1ESR2DRD2DRD3OPRK1 | |
| SCHEMBL7290410 | 0.73 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL5839879 | 0.73 | ESR1 (0.56) | ESR1ESR2DRD2DRD3OPRK1 | |
| SCHEMBL4193774 | 0.73 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL27849144 | 0.73 | ESR1 (0.56) | ESR1ESR2DRD2DRD3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772230-B2 | Chroman compound, processes for its preparation, and its pharmaceutical use | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2010-08-10 | — | — | US | disclosed |
| US-20080103307-A1 | Chroman Compound, Processes for Its Preparation, and Its Pharmaceutical Use | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103307-A1 | Chroman Compound, Processes for Its Preparation, and Its Pharmaceutical Use | KCNH1, HCN4, HCN1 | ESR1 3437/4885ESR2 4180/4885DRD2 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.