SCHEMBL6464770

SCHEMBL6464770

O=S(=O)(O)C1CCc2ccccc2O1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.49
SSTR4 P31391 1/20 0.38
HTR1A P08908 3/20 0.38
SIGMAR1 Q99720 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
NISCH Q9Y2I1 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
HTR1D P28221 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
CA1 P00915 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27984668 0.92 CA2 (0.44) CA2SSTR4HTR1ASIGMAR1ADRA2A
SCHEMBL4672085 0.83 CA2 (0.49) CA2SSTR4HTR1ASIGMAR1ADRA2A
SCHEMBL6591026 0.83 CA2 (0.56) CA2SSTR4HTR1ASIGMAR1ADRA2A
SCHEMBL11072331 0.82 HPGD (0.43) CA2NISCHMAOAMAOBHDAC3
Hydrochloric Acid SCHEMBL28080389 0.81 AOC2 (0.42) CA2NISCHMAOAMAOBHDAC3
SCHEMBL1365698 0.80 CA2 (0.47) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL2985307 0.79 ESR1 (0.55) CA2CA1
SCHEMBL8650215 0.79 CA2 (0.46) CA2SSTR4HTR1ASIGMAR1ADRA2A
SCHEMBL8650317 0.79 CA2 (0.49) CA2SSTR4HTR1ASIGMAR1ADRA2A
Hydrochloric Acid SCHEMBL30887472 0.78 ESR1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124687-A1 Process for synthesizing d-tocotrienols COULADOUROS ELIAS A (GR) 2005-06-09 US claimed
WO-2005035490-A2 PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS YASOO HEALTH, INC. (US) 2005-04-21 WO claimed
WO-2024144812-A1 PROCESS FOR THE PREPARATION OF DELTA-TOCOTRIENOL PEPTINOVO BIOPHARMA INC. (US) 2024-07-04 WO disclosed
WO-2024145566-A1 PROCESS FOR THE PREPARATION OF DELTA-TOCOTRIENOL PEPTINOVO BIOPHARMA, INC (US) 2024-07-04 WO disclosed
EP-4393913-A1 PROCESS FOR THE PREPARATION OF DELTA-TOCOTRIENOL Peptinovo Biopharma Inc. (US) 2024-07-03 EP disclosed
CN-103596564-B diphenylmethane derivatives as SGLT2 inhibitors GREEN CROSS CORP. (KR) 2016-05-04 CN disclosed
CN-104334535-A Dendrimer-like aminoamides with sodium channel blocking activity for the treatment of dry eye and other mucosal diseases PARION SCIENCES INC 2015-02-04 CN disclosed
CN-103415504-A 2-acyloxy-pyrrolin-4-ones BAYER IP GMBH 2013-11-27 CN disclosed
US-20050124687-A1 Process for synthesizing d-tocotrienols COULADOUROS ELIAS A (GR) 2005-06-09 US disclosed
WO-2005035490-A2 PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS YASOO HEALTH, INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124687-A1 Process for synthesizing d-tocotrienols UGT8, DDOST, GGPS1 CA2 4668/4885SSTR4 1760/4885HTR1A 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.