Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850213 | 0.95 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL28151755 | 0.91 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL14850246 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL13968275 | 0.87 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL14849974 | 0.87 | MAPT (0.44) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL298914 | 0.85 | P2RX1 (0.41) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL13836038 | 0.84 | KDM4E (0.40) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL297702 | 0.84 | MAPT (0.54) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL15073412 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 | |
| SCHEMBL13835559 | 0.83 | HTR1F (0.45) | ALDH1A1SMN1; SMN2LMNAHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366675-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2763966-B1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-04 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| CN-102414170-B | Insecticidal compounds | 先正达参股股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| EP-2763966-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050261-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013050261-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2427426-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127928-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010127928-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | ALDH1A1 331/4885SMN1; SMN2 1116/4885LMNA 868/4885 |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | ACHE, CDC25B, CYP1B1 | ALDH1A1 236/4885SMN1; SMN2 806/4885LMNA 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.