Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298535 | 0.84 | ALDH1A1 (0.40) | MAPTKMT2AMEN1TP53RAB9A | |
| SCHEMBL14850246 | 0.84 | ALDH1A1 (0.42) | MAPTKMT2AMEN1RAB9ARXFP1 | |
| SCHEMBL13968275 | 0.82 | ALDH1A1 (0.41) | MAPTKMT2AMEN1RAB9ARXFP1 | |
| SCHEMBL297830 | 0.82 | KDM4E (0.43) | MAPTKMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL298914 | 0.81 | P2RX1 (0.41) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL13835559 | 0.81 | HTR1F (0.45) | MAPTKMT2AMEN1POLBRAB9A | |
| SCHEMBL1275950 | 0.79 | KCNJ11 (0.36) | MAPTKMT2AMEN1TP53NPC1 | |
| SCHEMBL13977832 | 0.79 | HTT (0.38) | MAPTKMT2AMEN1POLBTP53 | |
| SCHEMBL13836282 | 0.79 | ALDH1A1 (0.42) | MAPTPOLBRAB9ARXFP1NPC1 | |
| SCHEMBL15073412 | 0.78 | ALDH1A1 (0.44) | MAPTKMT2AMEN1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427426-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |