Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.38 |
| ▸ | CALCR | P30988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548952 | 0.95 | KDM1A (0.48) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL29442098 | 0.93 | KDM1A (0.47) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL7351817 | 0.93 | MAPK8 (0.41) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL7351804 | 0.93 | MAPK8 (0.41) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL29607893 | 0.92 | KDM1A (0.48) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL30658576 | 0.92 | KDM1A (0.51) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL31031628 | 0.90 | MAPK8 (0.47) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL3865485 | 0.89 | MAPK8 (0.50) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL31165809 | 0.89 | MAPK8 (0.45) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL3215690 | 0.89 | MAPK8 (0.51) | KDM1AMAPK8MAPK9MAPK10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136555-A9 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2022-09-22 | — | — | WO | disclosed |