Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856443 | 0.86 | CNR2 (0.41) | KDM5AHDAC2HDAC6ROCK2 | |
| SCHEMBL29856214 | 0.86 | KDM5A (0.40) | KDM5ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29856177 | 0.83 | KDM5A (0.49) | KDM5ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29856242 | 0.83 | SRD5A2 (0.46) | KDM5AHDAC2HDAC6ROCK2MAPT | |
| SCHEMBL29856217 | 0.79 | TUBB4A (0.41) | KDM5ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29856503 | 0.75 | ADORA3 (0.44) | ROCK2EYA3MAPTHTTCYP19A1 | |
| SCHEMBL29856230 | 0.71 | ROCK2 (0.42) | HDAC2HDAC6ROCK2SLC22A12MAPT | |
| SCHEMBL29856340 | 0.71 | ROCK2 (0.38) | KDM5AHDAC2HDAC6ROCK2SLC22A12 | |
| SCHEMBL29856327 | 0.69 | KDM5A (0.48) | KDM5AROCK2SLC22A12EYA3 | |
| SCHEMBL16345008 | 0.69 | ROCK2 (0.62) | KDM5ATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |