Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 18/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 18/20 | 0.76 |
| ▸ | POLB | P06746 | 15/20 | 0.76 |
| ▸ | MAPT | P10636 | 13/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | RECQL | P46063 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 5/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993381 | 0.88 | MEN1 (0.60) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3012532 | 0.86 | MEN1 (1.00) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL26459002 | 0.84 | MAPT (1.00) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9911664 | 0.79 | MEN1 (0.62) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2302382 | 0.78 | KMT2A (0.62) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2302380 | 0.78 | KMT2A (0.62) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL6282463 | 0.75 | KMT2A (1.00) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3895245 | 0.75 | KMT2A (1.00) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3897789 | 0.75 | MEN1 (1.00) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3895249 | 0.75 | KMT2A (1.00) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466177-B2 | Treating and preventing viral infections | THE UAB RESEARCH FOUNDATION (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100286212-A1 | Treating and Preventing Viral Infections | THE UAB RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | US | disclosed |
| EP-2217573-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | The UAB Research Foundation (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009059243-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | THE UAB RESEARCH FOUNDATION (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | TYR, KRT18, MITF | MEN1 3959/4885KMT2A 82/4885POLB 1022/4885 |
| US-20100286212-A1 | Treating and Preventing Viral Infections | HAVCR2, IRF3, MAVS | MEN1 3172/4885KMT2A 3809/4885POLB 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.