Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856194 | 0.85 | SRD5A2 (0.47) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856267 | 0.84 | SRD5A2 (0.46) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856230 | 0.81 | ROCK2 (0.42) | CYP19A1HTTMEN1KMT2AMAPT | |
| SCHEMBL29856297 | 0.80 | MAPT (0.51) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL29856242 | 0.78 | SRD5A2 (0.46) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856187 | 0.77 | SRD5A2 (0.47) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856296 | 0.76 | PPARG (0.45) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856278 | 0.71 | SRD5A2 (0.48) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL29856212 | 0.71 | ADORA3 (0.40) | ALDH1A1MEN1KMT2AMAPTROCK2 | |
| SCHEMBL29856249 | 0.71 | SRD5A2 (0.47) | SRD5A2CYP19A1CYP11B1CYP11B2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |