Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856369 | 0.85 | SLC22A12 (0.48) | NTRK1POLBDYRK1ANFATC1GSK3B | |
| SCHEMBL29856145 | 0.82 | POLB (0.51) | NTRK1POLBDYRK1ANFATC1GSK3B | |
| SCHEMBL29856228 | 0.79 | ADORA3 (0.46) | POLBSLC22A12SLC22A6SLC22A8ADORA3 | |
| SCHEMBL29856185 | 0.77 | DYRK1A (0.51) | NTRK1DYRK1AGSK3BSLC22A12SLC22A6 | |
| SCHEMBL29856320 | 0.76 | POLB (0.48) | NTRK1POLBDYRK1ANFATC1GSK3B | |
| SCHEMBL12486373 | 0.75 | DYRK1A (0.53) | NTRK1POLBDYRK1ANFATC1GSK3B | |
| SCHEMBL29856173 | 0.75 | ADORA3 (0.40) | POLBSLC22A12SLC22A6SLC22A8ADORA3 | |
| SCHEMBL29856212 | 0.75 | ADORA3 (0.40) | POLBSLC22A12SLC22A6SLC22A8ADORA3 | |
| SCHEMBL29856189 | 0.75 | SLC22A12 (0.42) | POLBSLC22A12SLC22A6SLC22A8ADORA3 | |
| SCHEMBL22558992 | 0.74 | DYRK1A (0.51) | NTRK1POLBDYRK1ANFATC1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |