Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661772 | 0.83 | TLR8 (0.51) | TLR8ADORA1ADORA3KDM4EALDH1A1 | |
| SCHEMBL28499587 | 0.82 | ALDH1A1 (0.49) | TLR8ALDH1A1ADRA2AENPP2 | |
| SCHEMBL17401527 | 0.76 | ENPP2 (0.64) | TLR8ENPP2 | |
| SCHEMBL28499118 | 0.74 | ADRA2A (0.47) | TLR8ADRA2AENPP2 | |
| SCHEMBL28499593 | 0.70 | TSHR (0.46) | TLR8KDM4EMEN1ALDH1A1HTT | |
| SCHEMBL28497863 | 0.70 | ADRA2A (0.43) | TLR8MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL25437830 | 0.67 | CNR2 (0.42) | TLR8KDM4EMEN1ALDH1A1HTT | |
| SCHEMBL28502890 | 0.67 | TSHR (0.45) | ADORA2BKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL29856906 | 0.66 | ALDH1A1 (0.42) | ADORA2AADORA2BKDM4EMEN1ALDH1A1 | |
| SCHEMBL2943250 | 0.65 | TLR8 (0.70) | TLR8ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |