Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856754 | 0.82 | TLR8 (0.49) | ALDH1A1ENPP2TLR8ADRA2A | |
| SCHEMBL30661772 | 0.80 | TLR8 (0.51) | ALDH1A1TLR8TSHR | |
| SCHEMBL28499118 | 0.78 | ADRA2A (0.47) | ENPP2TLR8ADRA2A | |
| SCHEMBL4739176 | 0.76 | TSHR (0.50) | ALDH1A1TSHRADRA2A | |
| SCHEMBL8767485 | 0.75 | ALDH1A1 (0.56) | ALDH1A1GSK3B | |
| SCHEMBL17401500 | 0.74 | ENPP2 (0.77) | ENPP2 | |
| SCHEMBL10843846 | 0.73 | ALDH1A1 (0.59) | ALDH1A1GSK3BTLR8 | |
| SCHEMBL28497863 | 0.73 | ADRA2A (0.43) | ALDH1A1ENPP2TLR8ADRA2A | |
| SCHEMBL11788442 | 0.72 | ALDH1A1 (0.84) | ALDH1A1TLR8TSHR | |
| SCHEMBL10526480 | 0.70 | TSHR (0.74) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | disclosed |