Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.50 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859911 | 0.89 | MALT1 (0.51) | AKT1MALT1CMA1TACR1 | |
| SCHEMBL30225406 | 0.88 | AKT1 (0.45) | AKT1F2PRSS1ITGB1ITGA5 | |
| Acetic Acid SCHEMBL31076322 | 0.87 | AKT1 (0.47) | AKT1F2PRSS1ITGB1ITGA5 | |
| SCHEMBL30831830 | 0.85 | F2 (0.59) | AKT1F2PRSS1ITGB1ITGA5 | |
| SCHEMBL29387566 | 0.83 | F2 (0.57) | AKT1F2PRSS1ITGB1ITGA5 | |
| SCHEMBL29897716 | 0.82 | SIRT1 (0.60) | F2PRSS1 | |
| SCHEMBL31256537 | 0.81 | GRB2 (0.49) | AKT1MALT1ITGB1ITGA5 | |
| Acetic Acid SCHEMBL30041889 | 0.80 | CTSB (0.52) | F2 | |
| SCHEMBL9699194 | 0.79 | CMA1 (0.67) | CMA1TACR1 | |
| SCHEMBL1087489 | 0.79 | KDM1A (0.50) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720326-A1 | RECOMBINANT AMEBOCYTE CLOTTING FACTORS AND USES THEREOF | Charles River Laboratories, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20250002609-A1 | ANTI-KLK5 ANTIBODIES AND METHODS OF USE | GENENTECH, INC. (US) | 2025-01-02 | — | — | US | disclosed |
| US-12037412-B2 | Anti-KLK5 antibodies and methods of use | GENENTECH, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| EP-4291648-A1 | HYBRID AMEBOCYTE LYSATE AND USES THEREOF | Charles River Laboratories, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022174082-A1 | HYBRID AMEBOCYTE LYSATE AND USES THEREOF | CHARLES RIVER LABORATORIES, INC. (US) | 2022-08-18 | — | — | WO | disclosed |