Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748963 | 0.73 | ALOX5 (0.35) | KDM4EMAPT | |
| SCHEMBL27473717 | 0.72 | PRKCI (0.36) | KDM4EMAPT | |
| SCHEMBL2465458 | 0.70 | PRKCI (0.33) | — | |
| SCHEMBL29200838 | 0.70 | MAPKAPK2 (0.36) | HTT | |
| SCHEMBL28018125 | 0.70 | TNFSF11 (0.38) | KDM4E | |
| SCHEMBL27887045 | 0.70 | LMNA (0.39) | KDM4EMAPT | |
| SCHEMBL28007567 | 0.70 | LMNA (0.34) | KDM4EMAPT | |
| SCHEMBL23374468 | 0.68 | HTT (0.34) | HTT | |
| SCHEMBL4944664 | 0.68 | KDM4E (0.39) | KDM4EMAPT | |
| SCHEMBL27598250 | 0.68 | LMNA (0.33) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920731-A | Alpha-acetoxypyrazine acetamide compound and preparation method and application thereof | 山东大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114920731-A | Alpha-acetoxypyrazine acetamide compound and preparation method and application thereof | 山东大学 | 2022-08-19 | — | — | CN | disclosed |