Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360610 | 0.86 | GPR119 (0.47) | — | |
| SCHEMBL23360474 | 0.85 | FAAH (0.45) | LMNAALDH1A1CNR1CNR2OPRD1 | |
| SCHEMBL28437538 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23360508 | 0.81 | HTR3A (0.42) | LMNAALDH1A1CNR1CNR2KDM4E | |
| SCHEMBL23360357 | 0.81 | HTR3A (0.42) | LMNAALDH1A1CNR1CNR2KDM4E | |
| SCHEMBL23360358 | 0.81 | HTR3A (0.42) | LMNAALDH1A1CNR1CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL23360283 | 0.78 | SLC6A2 (0.47) | ALDH1A1OPRD1RAB9A | |
| SCHEMBL25231259 | 0.76 | SMO (0.36) | ALDH1A1OPRD1KCNH2 | |
| SCHEMBL23360644 | 0.73 | CHRNA7 (0.41) | ALDH1A1GSK3BHTR3A | |
| SCHEMBL23360178 | 0.73 | CHRNA7 (0.41) | ALDH1A1GSK3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |