Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SI | P14410 | 2/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299585 | 1.00 | MAPT (0.83) | MAPTTP53MGAMGAASI | |
| SCHEMBL19973935 | 0.80 | MGAM (0.65) | MAPTTP53MGAMGAASI | |
| SCHEMBL10835010 | 0.80 | MAPT (0.60) | MAPTTP53MGAMGAASI | |
| SCHEMBL8592636 | 0.80 | MAPT (0.65) | MAPTTP53MGAMGAASI | |
| SCHEMBL29885627 | 0.80 | MAPT (0.65) | MAPTTP53MGAMGAASI | |
| SCHEMBL31232976 | 0.78 | MGAM (0.66) | MAPTTP53MGAMGAASI | |
| SCHEMBL18662732 | 0.74 | MGAM (1.00) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL18662735 | 0.74 | MGAM (1.00) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL30040360 | 0.73 | MAPT (0.69) | MAPTTP53MGAMGAASI | |
| SCHEMBL3343111 | 0.73 | MAPT (0.69) | MAPTTP53MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073351-B | Preparation method of 3,3' -bisindolyl methane | 南京工业大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-115073351-A | Preparation method of 3,3' -bis-indolyl methane | 南京工业大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110408660-B | Method for synthesizing bisindole compound under catalysis of lipase | 南京工业大学 | 2022-09-16 | — | — | CN | disclosed |