Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299585 | 0.80 | MAPT (0.83) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL29862913 | 0.80 | MAPT (0.83) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL19973935 | 0.77 | MGAM (0.65) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL11376749 | 0.75 | GPR84 (0.50) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL10835824 | 0.74 | NR3C1 (0.52) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL10834681 | 0.73 | MAPT (0.56) | MAPTGAATP53MEN1KMT2A | |
| SCHEMBL1853638 | 0.73 | GPR84 (0.59) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL10836161 | 0.72 | NR3C1 (0.70) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL31232976 | 0.72 | MGAM (0.66) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL5642560 | 0.72 | GPR84 (0.58) | MAPTMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307898-A | INDOLES | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | claimed |
| EP-0035774-A2 | Indoles, process for preparing them and duplicating or marking systems containing them | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | claimed |
| US-4618684-A | Substituted indoles | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4485242-A | PRESSURE SENSITIVE CARBONLESS REPRODUCTION | STERLING DRUG INC. (US) | 1984-11-27 | — | — | US | disclosed |
| US-4307898-A | INDOLES | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0035774-A2 | Indoles, process for preparing them and duplicating or marking systems containing them | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | disclosed |