Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | SI | P14410 | 4/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31232976 | 0.83 | MGAM (0.66) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL6823826 | 0.83 | MEN1 (0.70) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL7299585 | 0.80 | MAPT (0.83) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL29862913 | 0.80 | MAPT (0.83) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL18662735 | 0.79 | MGAM (1.00) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL18662732 | 0.79 | MGAM (1.00) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL13253129 | 0.79 | MEN1 (0.74) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL10835010 | 0.77 | MAPT (0.60) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL19973394 | 0.76 | GAA (0.56) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL19973395 | 0.76 | GAA (0.56) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256502-A1 | ORGANIC COMPOUNDS | HOX THERAPEUTICS LIMITED (GB) | 2019-08-22 | — | — | US | disclosed |
| WO-2018051114-A1 | ORGANIC COMPOUNDS | HOX THERAPEUTICS LIMITED (GB) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256502-A1 | ORGANIC COMPOUNDS | POU2F1, BRIX1, PAX3 | MGAM 4464/4885GAA 4120/4885SI 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.