SCHEMBL29863071

SCHEMBL29863071

CCc1c(CC)c(N(CC)CC)c(CC)c(CC)c1-c1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
CYP3A4 P08684 3/20 0.47
TSHR P16473 2/20 0.47
PSMD14 O00487 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
GFER P55789 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 1/20 0.38
TP53 P04637 1/20 0.34
LMNA P02545 1/20 0.34
USP7 Q93009 5/20 0.33
PRKCI P41743 1/20 0.33
ACHE P22303 3/20 0.32
HSD17B10 Q99714 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596717 0.79 TDP1 (0.42) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Methane SCHEMBL28192521 0.77 TDP1 (0.40) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL7596728 0.69 ALDH1A1 (0.44) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL2155334 0.69 ALDH1A1 (0.86) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL8759737 0.67 ESR1 (0.42) ALDH1A1TDP1CYP3A4TP53USP7
Methane SCHEMBL28119679 0.67 GCGR (0.37) ALDH1A1TDP1CYP3A4SMN1; SMN2KDM4E
SCHEMBL33781 0.65 ALDH1A1 (1.00) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL8467252 0.65 ALDH1A1 (1.00) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Benzidine SCHEMBL25422776 0.63 TDP1 (0.73) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Benzidine SCHEMBL6160242 0.63 TDP1 (0.73) ALDH1A1TDP1L3MBTL1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901073-A Fungicidal combinations, mixtures and compositions and their use 阿达马蒂斯有限公司 2022-08-12 CN disclosed