Methane

Methane

SCHEMBL28192521

C.CCc1c(N)c(CC)c(CC)c(-c2ccc(N)cc2)c1CC

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.40
CYP3A4 P08684 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
USP7 Q93009 7/20 0.37
ACHE P22303 2/20 0.35
TAAR1 Q96RJ0 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 2/20 0.34
PSMD14 O00487 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.34
GFER P55789 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
HEXA P06865 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596717 0.98 TDP1 (0.42) TDP1CYP3A4ALDH1A1TP53USP7
Methane SCHEMBL28119679 0.80 GCGR (0.37) TDP1CYP3A4ALDH1A1TP53USP7
SCHEMBL29863071 0.77 ALDH1A1 (0.47) TDP1CYP3A4ALDH1A1TP53USP7
SCHEMBL2331006 0.75 GCGR (0.38) TDP1CYP3A4ALDH1A1TP53HSD17B10
SCHEMBL16405689 0.74 NOS3 (0.31)
SCHEMBL4592873 0.73 GCGR (0.41) ALDH1A1HSD17B10SMN1; SMN2MEN1MAPT
SCHEMBL29129796 0.72 CYP3A4 (0.42) TDP1CYP3A4ALDH1A1TP53USP7
SCHEMBL8759737 0.72 ESR1 (0.42) TDP1CYP3A4ALDH1A1TP53USP7
SCHEMBL27449057 0.71 DHFR (0.44) ALDH1A1TP53USP7MAPTKMT2A
SCHEMBL841170 0.71 NOS2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116560188-B Photosensitive resin composition, photosensitive resin sheet and application thereof 波米科技有限公司 2024-02-13 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
CN-107428895-A The method for preparing the porous material comprising catalyst system 巴斯夫欧洲公司 2017-12-01 CN disclosed