SCHEMBL7596728

SCHEMBL7596728

CCc1c(-c2ccc(N)cc2)ccc(N(CC)CC)c1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
PSMD14 O00487 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
GFER P55789 1/20 0.44
GAA P10253 3/20 0.34
MAPT P10636 3/20 0.34
TP53 P04637 1/20 0.32
USP7 Q93009 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
RARA P10276 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526892 0.77 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL11129444 0.77 TDP1 (0.39) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
Methane SCHEMBL28624868 0.75 TDP1 (0.37) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL4649425 0.74 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL5381204 0.71 USP7 (0.37) ALDH1A1CYP3A4TDP1L3MBTL1MAPK1
SCHEMBL2331008 0.71 MAPT (0.40) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL5386508 0.70 RPS6KA3 (0.38) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL17141911 0.70 CNR1 (0.38) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL29863071 0.69 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14
SCHEMBL395141 0.69 ALDH1A3 (0.38) ALDH1A1CYP3A4TDP1L3MBTL1PSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045276-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-18 EP claimed
US-20020127611-A1 Method for determination of water treatment polymers MW MONITORING IP LIMITED (GB) 2002-09-12 US disclosed
US-5968508-A NEUTRALIZATION OF PC-1 GLYCOPROTEIN; TREATING DIABETES REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE (US) 1999-10-19 US disclosed
US-5217691-A Complexing glucose with organic boron compound and indicator MILES INC. (US) 1993-06-08 US disclosed
EP-0542084-A1 Use of inhibitors of color generation in chromogenic assays Bayer Corporation (US) 1993-05-19 EP disclosed
US-5212066-A Semicarbazide, thiosemicarbazide and carbazide as inhibiitors of color generation MILES INC. (US) 1993-05-18 US disclosed
EP-0247457-B1 PROCESS FOR THE PREPARATION OF REAGENT LAYERS CONTAINING HYDROPHOBIC REAGENTS MILES INC. (US) 1993-04-07 EP disclosed
EP-0255708-B1 INDICATOR COMPOSITION AND METHOD FOR THE PREPARATION THEREOF MILES INC. (US) 1992-12-30 EP disclosed
US-5116763-A Borate buffer, ph indicator MILES INC. (US) 1992-05-26 US disclosed
US-5057276-A Dissolving ionomeric polymer and reagent in solvent, adding water, and removing solvent MILES INC. (US) 1991-10-15 US disclosed
EP-0247457-A2 Process for the preparation of reagent layers containing hydrophobic reagents MILES INC. (US) 1987-12-02 EP disclosed
EP-0230229-A2 Stable composition for the determination of peroxidatively active substances MILES INC. (US) 1987-07-29 EP disclosed
US-4621049-A Enzymatic high range glucose test MILES LABORATORIES, INC. (US) 1986-11-04 US disclosed
EP-0182225-A2 Enzymatic high range glucose test MILES INC. (US) 1986-05-28 EP disclosed
EP-0058334-B1 IMPROVED SYSTEM FOR THE DETERMINATION OF GLUCOSE IN FLUIDS MILES LABORATORIES, INC. (US) 1984-10-10 EP disclosed
US-4391906-A GLUCOSE OXIDASE, PEROXIDASE, M-ANISIDINE MILES LABORATORIES, INC. (US) 1983-07-05 US disclosed
US-4391905-A System for the determination of glucose in fluids MILES LABORATORIES, INC. (US) 1983-07-05 US disclosed
US-4385114-A DETERMINATION OF HYDROGEN PEROXIDE OR PEROXIDASE BOEHRINGER MANNHEIM GMBH (DE) 1983-05-24 US disclosed
EP-0058334-A1 Improved system for the determination of glucose in fluids MILES LABORATORIES, INC. (US) 1982-08-25 EP disclosed
US-4340669-A System for the determination of glucose in fluids MILES LABORATORIES, INC. (US) 1982-07-20 US disclosed